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ChatGPT in HEOR: A keen look at the future of the Healthcare Industry

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In November 2022, OpenAI, an artificial intelligence (AI) research and deployment company, announced the official launch of ChatGPT (generative pre-trained transformer). ChatGPT is a large language model from the GPT-3.5 series using chatbot with machine learning and AI. This model has been designed to conduct interactive chats and maintain the flow of discussion in a manner that mimics human conversations by using a natural language processing (NLP) system to respond to the user in a conversational format. The model is able to understand a situation and also learn from its previous interactions, making it a highly compliant technological system. The dialogue format enables ChatGPT to respond to any type of query, admit errors, disprove false assumptions, and reject irrelevant requests.

ChatGPT in the Healthcare system:

As huge volumes of modern healthcare data are becoming available with rapid turnover and complex structures, efficient methods are needed to promptly generate useful evidence. The traditional approaches are time-consuming and expensive, thus increasing the need for the application of AI and machine learning processes to synthesize healthcare data in order to address problems in a timely manner. ChatGPT can possibly meet these demands; therefore, in this article, we focus on the potential applications of ChatGPT to bring about automation, efficiency, and cost savings especially in health economics and outcomes research (HEOR).

ChatGPT in HEOR:

Health economics involves measuring and valuing the outcomes of healthcare interventions. Outcomes research comprises a set of scientific disciplines evaluating the effect of healthcare interventions on patients. Thus, as per ISPOR—The Professional Society for Health Economics and Outcomes Research, HEOR is the confluence of these two fields that work together to provide powerful data and insights for healthcare decision-makers. HEOR is essential in the healthcare ecosystem to avoid potential resource losses resulting from uneconomical practices. For example, it plays an important role in reducing patient healthcare costs by helping identify unnecessary procedures that may result in delayed treatments with resultant decrease in the survival or remission rates for certain diseases. ChatGPT can help healthcare researchers process and synthesize the rapidly growing data available in the medical field, which, in turn, can optimize the use of cost-effective treatments and strategies. Thus, ChatGPT is a potentially valuable addition to the HEOR toolkit. It can support the search for complex information from vast datasets, such as those generated by electronic health records (EHRs) or mobile devices, and can be used to improve detection and classification of diseases, to identify cohorts of patients sharing characteristics that might not be obvious when using traditional methods, and to predict the course of health outcomes under alternative personalized treatment options. Machine learning and deep learning in ChatGPT can be used for performing HEOR tasks as their role is to learn with experience and enhance the algorithm over time. This process of understanding and transforming enormous data into a specific and correct action to perform desired tasks can be beneficial in the healthcare industry. It can be used to efficiently perform analyses using a combination of datasets from epidemiologic surveys, claims datasets, patient surveys, and registries. The ChatGPT model updates result in real-time for users and can be potentially applied across healthcare systems of various regions (both national and international).

Thus, ChatGPT may be potentially applied in the HEOR field in the following areas:

● Disease diagnosis by identifying patients who are at risk for rapid-onset diseases; HEOR can assess the burden of illness when an underdiagnosis occurs.
● Treatment of diseases by initiating early treatment and determining new treatments for patients with diagnosed diseases.
● Disease progression assessment across a wide range of medical conditions by identifying patients who are at risk for rapid progression, assisting clinicians in detecting and supporting patients who may benefit from more advanced treatments and/or closer monitoring. HEOR professionals can use this technology to analyze the cost of delayed treatment.
● Patient adherence to treatment by identifying the main reasons for nonadherence in patients so as to design targeted strategies to improve patient adherence. The HEOR team can subsequently analyze patient data and summarize the effect of patient adherence to treatment on the reduction in healthcare costs. Such real-world evidence can pave the way for future improvement in strategies to improve patient treatment adherence.
● Reduction in hospital readmissions may be possible if healthcare professionals use predictive analytics to guide patients in their recovery phases or in preventable health conditions, thus also improving overall care. The HEOR system can additionally reduce overall hospital costs by evaluating the cause of such readmission.
● Adverse events (AE) management by promptly identifying patients who are at risk for experiencing an AE and the cost of potential AE in terms of HEOR.

The application of ChatGPT in the following key areas may potentially result in a massive transformation:

● Information management: Extensive data can be processed and analyzed in less time and at reduced costs.
● Pragmatic (real-world) clinical trials: Patients can be identified as per the trial requirements by analyzing information with advanced predictive analytics and also determining the ideal sample size for trials and for shortening the trial length.
● Digital therapeutics: Thorough information about individual patients can be provided, thus ensuring personalized and more effective treatments.
● Disease diagnosis and treatment: New diseases can be rapidly identified and new treatments can be swiftly introduced.
● Drug development: The development, efficiency, and production of life-saving drugs can be rapidly increased and they can be launched in the market with reduced costs.

When aptly used, ChatGPT can play a significant role in the healthcare industry, specifically in the field of HEOR.


Bioviser has a strong core team supporting the healthcare industry by simplifying data-driven projects like original research, meta-analysis, systematic review, manuscript writing, and so on. Further, the team often supports HEOR activities such as those discussed in the blog. Also, we have an expert team aiding the automation and digital transformation of simplified data to develop enhanced programs and optimize key pharmaceutical processes that help save both time and costs so that products can be introduced quickly, safely, and effectively in the market.

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This privacy policy was last updated on 25 January 2022.

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Haruyoshi Ogata

PRESIDENT - APAC OPERATIONS

Haruyoshi has had extensive experience working with key persons across pharmaceutical and medical device companies, publishers, editorial boards, international societies, and KOLs. With over 20 years of experience in business development and marketing across multiple industries, he has shared his expertise with many clients.

Haruyoshi has knowledge of publishing industries, business communication, and culture of Japan as well as the APAC region. As the manager of business development for a global publisher, he launched the science communication department. During this period, he conducted educational seminars for publication ethics and publication planning. He also has in-depth experiences as a branch manager in the publication industry of Australia for three years.

Haruyoshi has served as Director, Business Development, at one of the global medical communication agencies and has been involved in over 100 scientific publication projects and the launch of international journals. In addition, he has expertise in publication strategies, pub SOP, and policy developments.

Haruyoshi has been a part of the medical communications team (including medical writing) that aided pharmaceutical and medical device companies, which published work by Japanese clinical researches and studies in global journals. He has helped to publish several articles and supplements in journals.

K. G. Mathew Tharakan

VICE PRESIDENT - GOVERNMENT SOLUTIONS

Mathew has 30 years of experience in transportation operations and engineering management along with professional expertise in rail vehicle engineering at Southeastern Pennsylvania Transportation Authority (SEPTA). In 2016, he joined SEPTA’s business division as a Disadvantaged Business Enterprise Manager, overseeing the participation of minority and women-owned businesses in procurement and major construction contracts.

As part of a cost-saving strategy, Mathew was asked to set up a new material warranty department for SEPTA. He was additionally tasked with the rewriting of SOPs and policies for their supply chain division. For over three decades, he has occupied various Asian American leadership positions, particularly Indian American community leadership roles in Philadelphia and Bucks and Montgomery counties.

Mathew graduated from the 2013 Pennsylvania Political Leaders Fellowship Program (CPL), and has extensively travelled and researched the Pennsylvania political landscape. Nationally, he was involved in grassroot organizing, fundraising, faith-based initiatives, and President Obama’s Asian American affairs and White House community partnership program. Moreover, he has served as the president of Conference of Minority Transportation Officials, a national organization with 40 chapters across the United States that is committed to the diversity and progress of minorities in the transportation industry. He further co-chaired Mayor Kenney’s transportation and infrastructure transition committee and was appointed as a member of the mayor’s advisory commission on Asian American affairs in July 2016.

In 2018, Mathew was asked to serve on the Bucks county transportation commission to assist with the Middletown township’s traffic development program. He has an MBA in finance and a master’s in computer science from Philadelphia University. In addition, he has a bachelor’s degree in history and political science from Loyola College University, Madras, and a diploma in electrical technology from Kerala University.

At Bioviser, Mathew supports business development activities for government solutions with prime contractors for data analytics. He is presently working on his doctoral program in business administration with an emphasis in data analytics.

Roque Pereira

CHIEF FINANCIAL OFFICER (CFO)

Roque is a natural-born leader and has been successfully running a leading emergency and medical care practice for 27 years in Virginia, USA. Additionally, having earned his degree from Bombay Veterinary College in 1977, he has been actively practicing veterinary medicine for 44 years. Among his many achievements, Roque is a member of the DC Academy of Veterinary Medicine.

As a business owner, Roque has been safeguarding the vital assets of his company by reducing risks and accurately maintaining/closing books; operating an efficient and effective financial structure through planning, analysis, and remedial measures; strategizing in various ways to influence the future direction of his company; and stimulating and driving business growth initiatives such as improved company cost reduction, procurement, pricing execution, and other innovations adding value to the company. Additionally, he has been making decisions related to team recruitment and people management, patient records, and compliance to IRS and OSHA standards. Further, he has been regularly attending national and international conferences.

As the CFO at Bioviser, Roque is primarily responsible for providing financial leadership and aligning business and finance strategies to grow the business. When he is not working, Roque loves to garden, bike, visit national parks, and travel to other countries.

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Haruyoshi Ogata

PRESIDENT - APAC OPERATIONS

Haruyoshi has had extensive experience working with key persons across pharmaceutical and medical device companies, publishers, editorial boards, international societies, and KOLs. With over 20 years of experience in business development and marketing across multiple industries, he has shared his expertise with many clients.

Haruyoshi has knowledge of publishing industries, business communication, and culture of Japan as well as the APAC region. As the manager of business development for a global publisher, he launched the science communication department. During this period, he conducted educational seminars for publication ethics and publication planning. He also has in-depth experiences as a branch manager in the publication industry of Australia for three years.

Haruyoshi has served as Director, Business Development, at one of the global medical communication agencies and has been involved in over 100 scientific publication projects and the launch of international journals. In addition, he has expertise in publication strategies, pub SOP, and policy developments.

Haruyoshi has been a part of the medical communications team (including medical writing) that aided pharmaceutical and medical device companies, which published work by Japanese clinical researches and studies in global journals. He has helped to publish several articles and supplements in journals.

Keerti Bhagwat

SENIOR VICE PRESIDENT - FUNCTIONAL SERVICES

Keerti has over 24 years of experience in managing operations and delivery systems in the healthcare industry. Her strengths lie in building strategic relationships, strengthening client trust, and driving business diversification and organic growth. She has proficiently managed mid- to large-scale client accounts of top global pharmaceutical, biologics, and medical device organizations headquartered in the US, EU, and Japan.

Over the past two decades, Keerti has managed operations for end-to-end pharmacovigilance/drug safety case processing for global and local pharma companies for their global and local case submissions. She has successfully set up and strengthened delivery teams in India, Tokyo and Osaka in Japan, and Dalian and Shanghai in China.

With a strong inclination to weave technology into her processes, Keerti has built digital solutions for data entry (case processing) for low complex cases using various off-the-shelf RPA and AI applications. She has expertise in building processes, metrics and SLAs, and the overall delivery model suitable for case processing.

Keerti has led several strategic initiatives for initiation of new delivery site locations for Life Sciences and has successfully initiated new international sites in the US, Poland, Hungary, Germany, Philippines, Singapore, Japan, and China as well as Kolkata and Pune locations in India. She also has experience in delivering end-to-end projects (contracting to project confirmation to steady state) in collaboration with global teams.

Santhosh Sirupa

DIRECTOR - OPERATIONS

A pharmacist by qualification, Santhosh has a master’s degree in pharmaceutics from Cromwell College, UK. Also, he has an M.S. in general chemistry from MTSU, USA. At MTSU, he was awarded graduate assistantship for two years for achieving high GPAs. He has over 14 years of experience in managing operations and delivery systems in the clinical research and drug safety industry. He also has extensive experience in pharmacovigilance, data analysis, and clinical research. He has proven himself as a successful delivery manager with competent team management skills.

Over the last five years, Santhosh earned a reputation for providing scalable business operational solutions that meet demanding time constraints and exceed expectations. He has worked with numerous prestigious organizations such as Accenture, Novartis, Syneos Health (formerly known as InVentiv), and Cognizant Technology Solutions Pvt. Ltd. His expertise lies in streamlining quality operations and controlling and coordinating for the improvement of deliverables.

As an SME, Santhosh has sound knowledge of pharmacovigilance and regulatory activities. He is an experienced corporate global trainer who has trained over 150 associates in pharmacovigilance across the globe.

Santhosh has headed an independent quality control team at the portfolio level, has been responsible for multiple accounts, and has acted as a BQA (preparing for audits, facing client audits, conducting internal audits, and highlighting risks). He has been actively involved in determining, negotiating, and agreeing on in-house quality procedures, standards, and specifications as well as assessing customer requirements and ensuring that they are met. He has participated in important activities such as setting customer service standards, investigating and setting standards for quality, and ensuring that processes comply with standards at both national and international levels. He has closely worked with cross-functional teams to establish standards, systems and procedures, writing management and technical reports, and customer’s charters; to determine training needs; and to implement proposed CAPAs. He has acted as a catalyst for change and improvement in performance and quality.

Ivan Dsouza

CHIEF EXECUTIVE OFFICER (CEO)

Over the years, Ivan has built a solid multifunctional foundation in the healthcare industry, working at various leadership positions. He has lent his expertise to strategy, business and product offering expansion, team building, sales, delivery, client servicing, training and development, and recruitment.

With over 15 years of experience in business, Ivan has been a significant contributor to the growth of numerous businesses. He has consulted clients for clinical research solutions in India and has continued to grow such services in major markets like the US, EU, and Japan along with growing business regions such as China, Taiwan, South Korea, and India.

Ivan has built teams in these regions and extensively travelled to manage numerous customer relationships with budgets of millions of dollars. His strengths lie in customizing solutions; one of his greatest achievements was to design a customized business solution in pharmacovigilance with a novel partnering idea that won his company a deal of over $10M.

Beyond Bioviser, Ivan maintains an active presence in the industry ecosystem by being a member on numerous forums. He loves supporting and encouraging entrepreneurship. He also serves as a member of a few clinical research ventures’ advisory boards and helps accelerate their journey to commercial success. Despite several work commitments, Ivan loves to carve out time to share a wealth of knowledge with his industry peers and is a guest lecturer at various leading clinical research institutes. Additionally, he is a speaker at industry conferences on clinical research.